Preventive Photobiomodulation for Chemotherapy-Induced Oral Mucositis: A Systematic Review of Randomized Clinical Trials

Background/Objectives: Oral mucositis (OM) is the most common acute complication among cancer patients.It initially manifests as an inflammatory process, beginning with erythema and edema of the oral mucosa, progressing to erosive lesions, and ultimately leading to highly painful ulcers.This systematic review seeks to evaluate the efficacy of preve

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Revised time estimation of the ancestral human chromosome 2 fusion

Abstract Background The reduction of the chromosome number from 48 in the Great Apes to 46 in modern humans is thought to result from the end-to-end fusion of two ancestral non-human primate chromosomes forming the human chromosome 2 (HSA2).Genomic signatures of this event are the presence of inverted telomeric repeats at the HSA2 fusion site and a

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